Resistance mutation info of target

Target General Information
Target ID T56915
Target Name HIV Protease Target Info
Species Human immunodeficiency virus type 1 (HIV-1)
Uniprot ID POL_HV1B1(501-599)
Sequence PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF [Human immunodeficie
ncy virus type 1 (HIV-1)]
Drug Resistance Mutation and Corresponding Drugs
Mutation Info Missense: D30N
Drugs
Drug Name Nelfinavir Drug Info [1]
Targeted Disease HIV infection
Level of Resistance Confer high-level resistance to NFV
Mutation Info Missense: F53L
Drugs
Drug Name Nelfinavir Drug Info [2], [3], [4]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: G48A
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: G48L
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: G48M
Drugs
Drug Name Nelfinavir Drug Info [8], [9], [3]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Mutation Info Missense: G48Q
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: G48S
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: G48T
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: G48V
Drugs
Drug Name Nelfinavir Drug Info [4]
Targeted Disease HIV infection
Level of Resistance Confer intermediate-level resistance to NFV
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Mutation Info Missense: G73A
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: G73C
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: G73S
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: G73T
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I47A
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Mutation Info Missense: I47V
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Mutation Info Missense: I50L
Drugs
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: I50V
Drugs
Drug Name Nelfinavir Drug Info [5], [7]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I54A
Drugs
Drug Name Nelfinavir Drug Info [5], [7], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I54L
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I54M
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I54S
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I54T
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I54V
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: I84A
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: I84C
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: I84V
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: K20T
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: K65R
Drugs
Drug Name Nelfinavir Drug Info [18]
Targeted Disease HIV infection
Mutation Prevalence 7 out of 37 samples
Mutation Info Missense: L10F
Drugs
Drug Name Nelfinavir Drug Info [19], [20], [21]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV in vitro
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: L23I
Drugs
Drug Name Nelfinavir Drug Info [22]
Targeted Disease HIV infection
Level of Resistance Confer low/intermediate-level resistance to NFV
Mutation Info Missense: L24F
Drugs
Drug Name Nelfinavir Drug Info [23], [4]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV
Mutation Info Missense: L24I
Drugs
Drug Name Nelfinavir Drug Info [24]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: L33F
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Mutation Info Missense: L76V
Drugs
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: L89V
Drugs
Drug Name Nelfinavir Drug Info [2], [25], [26]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV
Mutation Info Missense: L90M
Drugs
Drug Name Nelfinavir Drug Info [27]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: L90M
Drugs
Drug Name Nelfinavir Drug Info [28]
Targeted Disease HIV infection
Mutation Prevalence 1 out of 31 samples
Mutation Info Missense: M36I + H69K + L89M
Drugs
Drug Name Tipranavir Drug Info [29]
Targeted Disease HIV infection
Mutation Info Missense: M41L
Drugs
Drug Name Tenofovir + Emtricitabine + Efavirenz Drug Info [30]
Targeted Disease HIV infection
Mutation Info Missense: M46*
Drugs
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Mutation Info Missense: M46I
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Mutation Info Missense: M46L
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Mutation Info Missense: M46V
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: N83D
Drugs
Drug Name Nelfinavir Drug Info [31], [4], [32]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: N88D
Drugs
Drug Name Nelfinavir Drug Info [33]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: N88G
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: N88S
Drugs
Drug Name Nelfinavir Drug Info [33]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance High-level resistance
Mutation Info Missense: N88T
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: Q58E
Drugs
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: T74P
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: T74S
Drugs
Drug Name Ritonavir Drug Info [34]
Targeted Disease HIV infection
Mutation Info Missense: V32I
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: V82A
Drugs
Drug Name Nelfinavir Drug Info [2]
Targeted Disease HIV infection
Level of Resistance Confer reduce susceptibility to NFV
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: V82C
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: V82F
Drugs
Drug Name Nelfinavir Drug Info [4]
Targeted Disease HIV infection
Level of Resistance Reduce susceptibility to NFV
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Darunavir + Ritonavir Drug Info [15], [5]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: V82L
Drugs
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: V82M
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [17]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Mutation Info Missense: V82S
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Mutation Info Missense: V82T
Drugs
Drug Name Nelfinavir Drug Info [5], [16]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Saquinavir + Ritonavir Drug Info [5], [6], [12]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Fosamprenavir + Ritonavir Drug Info [5], [14], [13]
Targeted Disease HIV infection
Level of Resistance Low-level resistance
Drug Name Tipranavir + Ritonavir Drug Info [5], [13]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Lopinavir + Ritonavir Drug Info [5], [10]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Indinavir + Ritonavir Drug Info [5], [12]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Drug Name Atazanavir + Ritonavir Drug Info [5], [11]
Targeted Disease HIV infection
Level of Resistance Intermediate resistance
Reference
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