Target General Infomation
Target ID
T86717
Former ID
TTDR00762
Target Name
3-dehydroquinate synthase
Gene Name
aroB
Synonyms
AROB; Dehydroquinatesynthase; aroB
Target Type
Research
BioChemical Class
Carbon-oxygen lyases
UniProt ID
EC Number
EC 4.2.3.4
Sequence
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQA
GVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQR
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELAS
GLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRA
GLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQ
SA
Inhibitor Carbaphosphonate Drug Info [551393]
Nicotinamide-Adenine-Dinucleotide Drug Info [551393]
Pathways
PANTHER Pathway Chorismate biosynthesis
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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