Target Information
Target General Infomation | |||||
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Target ID |
T21507
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Former ID |
TTDR00309
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Target Name |
Fatty acid-bindingprotein, epidermal
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Gene Name |
FABP5
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Synonyms |
E-FABP; Fatty Acid BindingProtein mal1; PA-FABP; Psoriasis-associated fatty acid-binding protein homolog; FABP5
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Target Type |
Research
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Function |
High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
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BioChemical Class |
Fatty acid bindingprotein
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Target Validation |
T21507
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UniProt ID | |||||
Sequence |
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC VMNNVTCTRIYEKVE |
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Pathways | |||||
KEGG Pathway | PPAR signaling pathway | ||||
NetPath Pathway | IL1 Signaling Pathway | ||||
Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | ||||
References |
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