Target Information
Target General Infomation | |||||
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Target ID |
T73694
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Former ID |
TTDR00884
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Target Name |
Tyrosine-protein kinase 6
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Gene Name |
PTK6
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Synonyms |
BRK; Breast tumor kinase; Brk (PTK6); Tyrosine-protein kinase brk; PTK6
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Target Type |
Research
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Function |
Isoform 2 inhibits PTK6 phosphorylation and PTK6 association with other tyrosine-phosphorylated proteins.
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BioChemical Class |
Kinase
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UniProt ID | |||||
EC Number |
EC 2.7.10.2
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Sequence |
MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQG
YVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRD TQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPLPH WDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMK KLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGM CYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALS RGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLM LTCWCRDPEQRPCFKALRERLSSFTSYENPT |
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Pathways | |||||
WikiPathways | EGF/EGFR Signaling Pathway | ||||
Focal Adhesion | |||||
References |
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