Drug Information
Drug General Information | |||||
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Drug ID |
DX2HI8
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Drug Name |
(6,7-Dimethyl-quinazolin-4-yl)-methyl-m-tolyl-amine; hydrochloride
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Synonyms |
CHEMBL554566
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Indication | Discovery agent | Investigative | [1] | ||
Formula |
C18H20ClN3
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Canonical SMILES |
Cl.CN(c1cccc(C)c1)c2ncnc3cc(C)c(C)cc23
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InChI |
InChI=1S/C18H19N3.ClH/c1-12-6-5-7-15(8-12)21(4)18-16-9-13(2)14(3)10-17(16)19-11-20-18;/h5-11H,1-4H3;1H
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InChIKey |
SOWYIIFCVPQQBN-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Epidermal growth factor receptor III | Target Info | [1] | ||
Macrophage colony-stimulating factor 1 | Target Info | [1] | |||
KEGG Pathway | Ras signaling pathway | ||||
Rap1 signaling pathway | |||||
Cytokine-cytokine receptor interaction | |||||
PI3K-Akt signaling pathway | |||||
Osteoclast differentiation | |||||
Hematopoietic cell lineage | |||||
TNF signaling pathway | |||||
Rheumatoid arthritis | |||||
NetPath Pathway | TSH Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
EGFR1 Signaling Pathway | |||||
TGF_beta_Receptor Signaling Pathway | |||||
Pathway Interaction Database | Signaling events mediated by PTP1B | ||||
Signaling events mediated by TCPTP | |||||
Integrins in angiogenesis | |||||
WikiPathways | Cytokines and Inflammatory Response | ||||
Hematopoietic Stem Cell Differentiation | |||||
Differentiation Pathway | |||||
miR-targeted genes in muscle cell - TarBase | |||||
Folate Metabolism | |||||
References | |||||
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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