Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXU0BL
|
||||
| Drug Name |
(R)-2-{3'-[2-(3-dimethylamino-pyrrolidin-1-yl)-thiazol-4-yl]-biphenyl-yl}-4-methyl-pentanoic acid cyanomethyl-amide
|
||||
| Synonyms |
CHEMBL213244
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H35N5OS
|
||||
| Canonical SMILES |
CC(C)C[C@@H](C(=O)NCC#N)c1cccc(c1)c2cccc(c2)c3csc(n3)N4CCC(C4)N(C)C
|
||||
| InChI |
InChI=1S/C29H35N5OS/c1-20(2)15-26(28(35)31-13-12-30)23-9-5-7-21(16-23)22-8-6-10-24(17-22)27-19-36-29(32-27)34-14-11-25(18-34)33(3)4/h5-10,16-17,19-20,25-26H,11,13-15,18H2,1-4H3,(H,31,35)/t25?,26-/m1/s1
|
||||
| InChIKey |
SZQZHZOCBPSZIO-FXDYGKIASA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.