Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3PVO
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| Drug Name |
(R)-4-Dicyclohexylcarbamoyl-4-[(1H-indole-2-carbonyl)-amino]-butyric acid
|
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| Synonyms |
CHEMBL422873
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| Indication | Discovery agent | Investigative | [1] | ||
| Formula |
C26H35N3O4
|
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| Canonical SMILES |
OC(=O)CC[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N(C3CCCCC3)C4CCCCC4
|
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| InChI |
InChI=1S/C26H35N3O4/c30-24(31)16-15-22(28-25(32)23-17-18-9-7-8-14-21(18)27-23)26(33)29(19-10-3-1-4-11-19)20-12-5-2-6-13-20/h7-9,14,17,19-20,22,27H,1-6,10-13,15-16H2,(H,28,32)(H,30,31)/t22-/m0/s1
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| InChIKey |
OKFKXUMMUSRABT-QFIPXVFZSA-N
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| Target and Pathway | |||||
| Target(s) | Gastrin/cholecystokinin type B receptor | Target Info | [1] | ||
| Cholecystokinin receptor type A | Target Info | [1] | |||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gastric acid secretionhsa04020:Calcium signaling pathway | |||||
| Insulin secretion | |||||
| Pancreatic secretion | |||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like | |||||
| References | |||||
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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