Drug Information

Drug General Information
Drug ID
DXE95B
Drug Name
(S)-2-(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chlorobenzamido)-3-(4-chlorophenyl)propanoic acid
Synonyms
CHEMBL584259
Indication Discovery agent Investigative [1587926]
Formula
C22H16Cl2N4O5S2
Canonical SMILES
OC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)c2ccc(Cl)cc2NS(=O)(=O)c3cccc4nsnc34
InChI
InChI=1S/C22H16Cl2N4O5S2/c23-13-6-4-12(5-7-13)10-18(22(30)31)25-21(29)15-9-8-14(24)11-17(15)28-35(32,33)19-3-1-2-16-20(19)27-34-26-16/h1-9,11,18,28H,10H2,(H,25,29)(H,30,31)/t18-/m0/s1
InChIKey
QPAIWOSZQHLQDZ-SFHVURJKSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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