Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5QVI
|
||||
| Drug Name |
(S)-2-(6-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(5-fluoroindolin-1-yl)-4-(methylsulfonyl)butan-2-yl)propanamide
|
||||
| Synonyms |
CHEMBL205240
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H36ClFN4O4S
|
||||
| Canonical SMILES |
CS(=O)(=O)CC[C@@H](CN1CCc2cc(F)ccc12)NC(=O)[C@H](CC3CCCCC3)Nc4oc5cc(Cl)ccc5n4
|
||||
| InChI |
InChI=1S/C29H36ClFN4O4S/c1-40(37,38)14-12-23(18-35-13-11-20-16-22(31)8-10-26(20)35)32-28(36)25(15-19-5-3-2-4-6-19)34-29-33-24-9-7-21(30)17-27(24)39-29/h7-10,16-17,19,23,25H,2-6,11-15,18H2,1H3,(H,32,36)(H,33,34)/t23-,25-/m0/s1
|
||||
| InChIKey |
FSXZTYDYWLKOJJ-ZCYQVOJMSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.