Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXF4OZ
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| Drug Name |
(S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(3-(methylsulfonyl)phenylamino)propan-2-yl)propanamide
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| Synonyms |
CHEMBL380832
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H33ClN4O4S
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| Canonical SMILES |
C[C@@H](CNc1cccc(c1)S(=O)(=O)C)NC(=O)[C@H](CC2CCCCC2)Nc3oc4c(Cl)cccc4n3
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| InChI |
InChI=1S/C26H33ClN4O4S/c1-17(16-28-19-10-6-11-20(15-19)36(2,33)34)29-25(32)23(14-18-8-4-3-5-9-18)31-26-30-22-13-7-12-21(27)24(22)35-26/h6-7,10-13,15,17-18,23,28H,3-5,8-9,14,16H2,1-2H3,(H,29,32)(H,30,31)/t17-,23-/m0/s1
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| InChIKey |
AIWUIXXWTABHNR-SBUREZEXSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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