Drug Information

Drug General Information
Drug ID
DXT4VN
Drug Name
(S)-2-Amino-1-(4-{2-[4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidin-1-yl)-4-methylsulfanyl-butan-1-one
Synonyms
CHEMBL172561
Indication Discovery agent Investigative [1587926]
Formula
C30H40ClN5O2S
Canonical SMILES
CSCC[C@H](N)C(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)CC1
InChI
InChI=1S/C30H40ClN5O2S/c1-39-18-10-26(32)30(38)36-12-8-21(9-13-36)19-27(37)34-14-16-35(17-15-34)29-25-7-6-24(31)20-23(25)5-4-22-3-2-11-33-28(22)29/h2-3,6-7,11,20-21,26,29H,4-5,8-10,12-19,32H2,1H3/t26-,29?/m0/s1
InChIKey
ROEOSNLXLMWGPJ-QUWDGAPNSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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