Drug Information
Drug General Information | |||||
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Drug ID |
DXTU6Y
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Drug Name |
(S)-3-Bromo-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide
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Synonyms |
CHEMBL1907851
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Indication | Discovery agent | Investigative | [1] | ||
Formula |
C23H17BrFN3O2
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Canonical SMILES |
CN1C(=O)[C@@H](NC(=O)c2cccc(Br)c2)N=C(c3ccccc3F)c4ccccc14
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InChI |
InChI=1S/C23H17BrFN3O2/c1-28-19-12-5-3-10-17(19)20(16-9-2-4-11-18(16)25)26-21(23(28)30)27-22(29)14-7-6-8-15(24)13-14/h2-13,21H,1H3,(H,27,29)/t21-/m1/s1
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InChIKey |
PSNAHSRRFJSWQU-OAQYLSRUSA-N
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Target and Pathway | |||||
Target(s) | Gastrin/cholecystokinin type B receptor | Target Info | [1] | ||
Cholecystokinin receptor type A | Target Info | [1] | |||
KEGG Pathway | Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Gastric acid secretionhsa04020:Calcium signaling pathway | |||||
Insulin secretion | |||||
Pancreatic secretion | |||||
PANTHER Pathway | CCKR signaling map ST | ||||
PathWhiz Pathway | Gastric Acid Production | ||||
Reactome | Peptide ligand-binding receptors | ||||
G alpha (q) signalling events | |||||
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors | |||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | |||||
Secretion of Hydrochloric Acid in Parietal Cells | |||||
Peptide GPCRs | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like | |||||
References | |||||
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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