Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXTY9B
|
||||
| Drug Name |
(S)-ethyl 3-(4-cyclohexyl-2-(3-methoxybenzamido)butanamido)-4-(5-fluoroindolin-1-yl)butanoate
|
||||
| Synonyms |
CHEMBL383469
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C32H42FN3O5
|
||||
| Canonical SMILES |
CCOC(=O)C[C@@H](CN1CCc2cc(F)ccc12)NC(=O)[C@H](CCC3CCCCC3)NC(=O)c4cccc(OC)c4
|
||||
| InChI |
InChI=1S/C32H42FN3O5/c1-3-41-30(37)20-26(21-36-17-16-23-18-25(33)13-15-29(23)36)34-32(39)28(14-12-22-8-5-4-6-9-22)35-31(38)24-10-7-11-27(19-24)40-2/h7,10-11,13,15,18-19,22,26,28H,3-6,8-9,12,14,16-17,20-21H2,1-2H3,(H,34,39)(H,35,38)/t26-,28-/m0/s1
|
||||
| InChIKey |
VUNCDQVIHHNTRK-XCZPVHLTSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.