Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXPP0H
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| Drug Name |
(S)-N-((R)-2-(benzyloxy)-1-cyanoethyl)-4-methyl-2-(2-(5-methyl-1H-imidazol-4-yl)acetamido)pentanamide
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| Synonyms |
CHEMBL208359
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H29N5O3
|
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)Cc1[nH]cnc1C)C(=O)N[C@@H](COCc2ccccc2)C#N
|
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| InChI |
InChI=1S/C22H29N5O3/c1-15(2)9-20(27-21(28)10-19-16(3)24-14-25-19)22(29)26-18(11-23)13-30-12-17-7-5-4-6-8-17/h4-8,14-15,18,20H,9-10,12-13H2,1-3H3,(H,24,25)(H,26,29)(H,27,28)/t18-,20+/m1/s1
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| InChIKey |
XMXQTAXOTWDYTP-QUCCMNQESA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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