Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXE9MN
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| Drug Name |
(S)-N-((S)-3-cyclohexyl-1-oxo-1-((S)-1-(4-(trifluoromethoxy)phenylamino)propan-2-ylamino)propan-2-yl)-tetrahydrofuran-2-carboxamide
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| Synonyms |
CHEMBL214897
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H34F3N3O4
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| Canonical SMILES |
C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC2CCCCC2)NC(=O)[C@@H]3CCCO3
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| InChI |
InChI=1S/C24H34F3N3O4/c1-16(15-28-18-9-11-19(12-10-18)34-24(25,26)27)29-22(31)20(14-17-6-3-2-4-7-17)30-23(32)21-8-5-13-33-21/h9-12,16-17,20-21,28H,2-8,13-15H2,1H3,(H,29,31)(H,30,32)/t16-,20-,21-/m0/s1
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| InChIKey |
JZPVDDNAUOMUOJ-NDXORKPFSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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