Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXK9L9
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| Drug Name |
(S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-1,3-dimethyl-1H-pyrazole-4-carboxamide
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| Synonyms |
CHEMBL556421
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C17H18ClN5O2
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| Canonical SMILES |
Cc1nn(C)cc1C(=O)N[C@@H](Cc2cccc(Cl)c2)C(=O)NCC#N
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| InChI |
InChI=1S/C17H18ClN5O2/c1-11-14(10-23(2)22-11)16(24)21-15(17(25)20-7-6-19)9-12-4-3-5-13(18)8-12/h3-5,8,10,15H,7,9H2,1-2H3,(H,20,25)(H,21,24)/t15-/m0/s1
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| InChIKey |
MYBHYCWWPQBNSP-HNNXBMFYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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