Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXE4UE
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| Drug Name |
[(S)-1-((3R,4S)-2-Oxo-4-phenylsulfanyl-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester
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| Synonyms |
CHEMBL31788
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H25N3O4S
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| Canonical SMILES |
O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]2[C@@H](NC2=O)Sc3ccccc3)OCc4ccccc4
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| InChI |
InChI=1S/C26H25N3O4S/c30-23(28-22-24(31)29-25(22)34-20-14-8-3-9-15-20)21(16-18-10-4-1-5-11-18)27-26(32)33-17-19-12-6-2-7-13-19/h1-15,21-22,25H,16-17H2,(H,27,32)(H,28,30)(H,29,31)/t21-,22+,25-/m0/s1
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| InChIKey |
LKVLCOTZWXWKQV-FBLLAGFSSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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