Drug Information

Drug General Information
Drug ID
DX0Q7M
Drug Name
1-[4-((R)-3-Bromo-10-methoxy-8-methyl-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone
Synonyms
CHEMBL56774
Indication Discovery agent Investigative [1587926]
Formula
C28H30BrN3O3
Canonical SMILES
COc1cc(C)cc2CCc3cc(Br)cnc3[C@H](C4CCN(CC4)C(=O)Cc5cc[n+]([O-])cc5)c12
InChI
InChI=1S/C28H30BrN3O3/c1-18-13-21-3-4-22-16-23(29)17-30-28(22)27(26(21)24(14-18)35-2)20-7-9-31(10-8-20)25(33)15-19-5-11-32(34)12-6-19/h5-6,11-14,16-17,20,27H,3-4,7-10,15H2,1-2H3/t27-/m1/s1
InChIKey
QWIZYRGWEQXHJG-HHHXNRCGSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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