Drug Information

Drug General Information
Drug ID
DX9TLP
Drug Name
1-[4-(8-Chloro-3-thiocyanato-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone
Synonyms
CHEMBL334834
Indication Discovery agent Investigative [1587926]
Formula
C27H23ClN4OS
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)C(=O)Cc4ccncc4)c5ncc(SC#N)cc5CCc2c1
InChI
InChI=1S/C27H23ClN4OS/c28-22-3-4-24-20(14-22)1-2-21-15-23(34-17-29)16-31-27(21)26(24)19-7-11-32(12-8-19)25(33)13-18-5-9-30-10-6-18/h3-6,9-10,14-16H,1-2,7-8,11-13H2
InChIKey
DYSOHBRXQUBMIP-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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