Drug Information

Drug General Information
Drug ID
DXD0RD
Drug Name
1-{4-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carbonyl]-cyclohexyl}-ethanone
Synonyms
CHEMBL422723
Indication Discovery agent Investigative [1587926]
Formula
C27H32ClN3O2
Canonical SMILES
CC(=O)C1CCC(CC1)C(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35
InChI
InChI=1S/C27H32ClN3O2/c1-18(32)19-4-7-21(8-5-19)27(33)31-15-13-30(14-16-31)26-24-11-10-23(28)17-22(24)9-6-20-3-2-12-29-25(20)26/h2-3,10-12,17,19,21,26H,4-9,13-16H2,1H3
InChIKey
GYYWBOZTAUCCFO-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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