Drug Information

Drug General Information
Drug ID
DX0JRV
Drug Name
15,16-dibenzyl-17-oxo-(16R)-2-oxa-9,11,15,18-tetraazapentacyclo[17.6.2.13,7.09,13.023,27]octacosa-1(26),3,5,7(28),10,12,19(27),20,22,24-decaen-4-yl cyanide
Synonyms
CHEMBL299621
Indication Discovery agent Investigative [1587926]
Formula
C38H31N5O2
Canonical SMILES
O=C1Nc2cccc3ccc(Oc4cc(Cn5cncc5CN(Cc6ccccc6)[C@@H]1Cc7ccccc7)ccc4C#N)cc23
InChI
InChI=1S/C38H31N5O2/c39-21-31-15-14-29-19-37(31)45-33-17-16-30-12-7-13-35(34(30)20-33)41-38(44)36(18-27-8-3-1-4-9-27)42(23-28-10-5-2-6-11-28)25-32-22-40-26-43(32)24-29/h1-17,19-20,22,26,36H,18,23-25H2,(H,41,44)/t36-/m1/s1
InChIKey
QIQWUVXAQGNSCR-PSXMRANNSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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