| Drug General Information |
| Drug ID |
DXD5PR
|
| Drug Name |
2-(1H-indazol-3-yl)-1H-benzo[d]imidazole
|
| Synonyms |
CHEMBL383990
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C14H10N4
|
| Canonical SMILES |
c1ccc2[nH]c(nc2c1)c3n[nH]c4ccccc34
|
| InChI |
InChI=1S/C14H10N4/c1-2-6-10-9(5-1)13(18-17-10)14-15-11-7-3-4-8-12(11)16-14/h1-8H,(H,15,16)(H,17,18)
|
| InChIKey |
JTKFRFMSUBOCIQ-UHFFFAOYSA-N
|
| Target and Pathway |
| Target(s) |
Vascular endothelial growth factor receptor 1 |
Target Info |
|
[1]
|
|---|
| Basic fibroblast growth factor receptor 1 |
Target Info |
|
[1]
|
|
KEGG Pathway
|
Ras signaling pathway
|
|
Rap1 signaling pathway
|
|
Cytokine-cytokine receptor interaction
|
|
HIF-1 signaling pathway
|
|
Endocytosis
|
|
PI3K-Akt signaling pathway
|
|
Focal adhesion
|
|
Transcriptional misregulation in cancer
|
|
Rheumatoid arthritishsa04010:MAPK signaling pathway
|
|
Adherens junction
|
|
Signaling pathways regulating pluripotency of stem cells
|
|
Regulation of actin cytoskeleton
|
|
Pathways in cancer
|
|
Proteoglycans in cancer
|
|
Prostate cancer
|
|
Melanoma
|
|
Central carbon metabolism in cancer
|
|
NetPath Pathway
|
TCR Signaling Pathway
|
|
PANTHER Pathway
|
Angiogenesis
|
|
FGF signaling pathway
|
|
Pathway Interaction Database
|
Glypican 1 network
|
|
HIF-2-alpha transcription factor network
|
|
S1P3 pathway
|
|
VEGF and VEGFR signaling network
|
|
VEGFR1 specific signals
|
|
Signaling events mediated by VEGFR1 and VEGFR2glypican_1pathway:Glypican 1 network
|
|
Syndecan-4-mediated signaling events
|
|
N-cadherin signaling events
|
|
FGF signaling pathway
|
|
Reactome
|
Neurophilin interactions with VEGF and VEGFR
|
|
VEGF binds to VEGFR leading to receptor dimerization
|
|
WikiPathways
|
Focal Adhesion
|
|
Signaling by VEGF
|
|
AngiogenesisWP51:Regulation of Actin Cytoskeleton
|
|
Endochondral Ossification
|
|
MAPK Signaling Pathway
|
|
Mesodermal Commitment Pathway
|
|
Hair Follicle Development: Induction (Part 1 of 3)
|
|
Integrated Pancreatic Cancer Pathway
|
|
Signaling Pathways in Glioblastoma
|
|
Neural Crest Differentiation
|
|
Signaling by FGFR
|
| References |
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |
|---|
