Drug Information

Drug General Information
Drug ID
DX7JZE
Drug Name
2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(3-phenyl-propionyl)-piperazin-2-yl]-N-pyridin-3-ylmethyl-acetamide
Synonyms
CHEMBL425216
Indication Discovery agent Investigative [1587926]
Formula
C35H35BrClN5O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(CC(=O)NCc4cccnc4)C3)C(=O)CCc5ccccc5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C35H35BrClN5O2/c36-28-17-27-10-9-26-18-29(37)11-12-31(26)35(34(27)40-22-28)41-15-16-42(33(44)13-8-24-5-2-1-3-6-24)30(23-41)19-32(43)39-21-25-7-4-14-38-20-25/h1-7,11-12,14,17-18,20,22,30,35H,8-10,13,15-16,19,21,23H2,(H,39,43)
InChIKey
CJNVALOLKPITKX-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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