Drug Information

Drug General Information
Drug ID
DXE4MJ
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-nitro-phenyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL158245
Indication Discovery agent Investigative [1587926]
Formula
C27H22BrClN6O2
Canonical SMILES
[O-][N+](=O)c1ccc(N\\C(=N/C#N)\\N2CCC(=C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC2)cc1
InChI
InChI=1S/C27H22BrClN6O2/c28-20-13-19-2-1-18-14-21(29)3-8-24(18)25(26(19)31-15-20)17-9-11-34(12-10-17)27(32-16-30)33-22-4-6-23(7-5-22)35(36)37/h3-8,13-15H,1-2,9-12H2,(H,32,33)
InChIKey
VUMYTLOVNOKNAO-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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