Drug Information

Drug General Information
Drug ID
DXU1YR
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-pyridin-2-ylmethyl-piperidine-1-carboxamidine
Synonyms
CHEMBL345575
Indication Discovery agent Investigative [1587926]
Formula
C27H24BrClN6
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/Cc4ccccn4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C27H24BrClN6/c28-21-13-20-5-4-19-14-22(29)6-7-24(19)25(26(20)32-15-21)18-8-11-35(12-9-18)27(34-17-30)33-16-23-3-1-2-10-31-23/h1-3,6-7,10,13-15H,4-5,8-9,11-12,16H2,(H,33,34)
InChIKey
PMQORWKGWDLDEI-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.