Drug Information

Drug General Information
Drug ID
DXR4SU
Drug Name
4-(3-Chloro-phenyl)-6-[1-(4-chloro-phenyl)-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-1-methyl-1H-quinolin-2-one
Synonyms
CHEMBL137087
Indication Discovery agent Investigative [1587926]
Formula
C28H23Cl2N3O
Canonical SMILES
CN1C(=O)C=C(c2cccc(Cl)c2)c3cc(ccc13)C(C)(c4ccc(Cl)cc4)c5cncn5C
InChI
InChI=1S/C28H23Cl2N3O/c1-28(26-16-31-17-32(26)2,19-7-10-21(29)11-8-19)20-9-12-25-24(14-20)23(15-27(34)33(25)3)18-5-4-6-22(30)13-18/h4-17H,1-3H3
InChIKey
AOAQWAKHGOYQKE-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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