Drug Information
| Drug General Information | |||||
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| Drug ID |
DXTJ2K
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| Drug Name |
4-(5-{[[1-(3-Chloro-benzyl)-2-oxo-pyrrolidin-3-yl]-(2-piperazin-1-yl-ethyl)-amino]-methyl}-imidazol-1-ylmethyl)-benzonitrile
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| Synonyms |
CHEMBL101788
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| Indication | Discovery agent | Investigative | [1] | ||
| Formula |
C29H34ClN7O
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| Canonical SMILES |
Clc1cccc(CN2CC[C@H](N(CCN3CCNCC3)Cc4cncn4Cc5ccc(cc5)C#N)C2=O)c1
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| InChI |
InChI=1S/C29H34ClN7O/c30-26-3-1-2-25(16-26)20-36-11-8-28(29(36)38)35(15-14-34-12-9-32-10-13-34)21-27-18-33-22-37(27)19-24-6-4-23(17-31)5-7-24/h1-7,16,18,22,28,32H,8-15,19-21H2/t28-/m0/s1
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| InChIKey |
OAOZPXOXMVMQBZ-NDEPHWFRSA-N
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| Target and Pathway | |||||
| Target(s) | Farnesyltransferase | Target Info | [1] | ||
| Protein farnesyltransferase beta subunit | Target Info | [1] | |||
| KEGG Pathway | Terpenoid backbone biosynthesis | ||||
| Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis | |||||
| Biosynthesis of antibiotics | |||||
| NetPath Pathway | TSH Signaling Pathway | ||||
| Reactome | Apoptotic cleavage of cellular proteins | ||||
| Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade | |||||
| WikiPathways | Visual phototransduction | ||||
| Apoptotic execution phaseWP2776:Visual phototransduction | |||||
| References | |||||
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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