Drug General Information |
Drug ID |
DX2RCS
|
Drug Name |
4-[2-(4-hydroxyphenyl)-1-[6-methyl(3-pentylsulfanylpropyl)aminohexyl]-(E)-1-butenyl]phenol
|
Synonyms |
CHEMBL184285
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Formula |
C31H47NO2S
|
Canonical SMILES |
CCCCCSCCCN(C)CCCCCC\\C(=C(\\CC)/c1ccc(O)cc1)\\c2ccc(O)cc2
|
InChI |
InChI=1S/C31H47NO2S/c1-4-6-11-24-35-25-12-23-32(3)22-10-8-7-9-13-31(27-16-20-29(34)21-17-27)30(5-2)26-14-18-28(33)19-15-26/h14-21,33-34H,4-13,22-25H2,1-3H3/b31-30+
|
InChIKey |
ALXFBXZUXCHLTA-NVQSTNCTSA-N
|
Target and Pathway |
Target(s) |
Estrogen receptor beta |
Target Info |
|
[1]
|
Estrogen receptor |
Target Info |
|
[1]
|
KEGG Pathway
|
Estrogen signaling pathway
|
Prolactin signaling pathwayhsa04915:Estrogen signaling pathway
|
Prolactin signaling pathway
|
Thyroid hormone signaling pathway
|
Endocrine and other factor-regulated calcium reabsorption
|
Proteoglycans in cancer
|
NetPath Pathway
|
FSH Signaling Pathway
|
EGFR1 Signaling Pathway
|
RANKL Signaling Pathway
|
Pathway Interaction Database
|
Plasma membrane estrogen receptor signaling
|
Validated nuclear estrogen receptor beta network
|
Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
|
Signaling events mediated by HDAC Class II
|
LKB1 signaling events
|
Regulation of Telomerase
|
ATF-2 transcription factor network
|
AP-1 transcription factor network
|
FOXM1 transcription factor network
|
Validated nuclear estrogen receptor alpha network
|
Signaling mediated by p38-alpha and p38-beta
|
FOXA1 transcription factor network
|
Reactome
|
Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
|
Nuclear Receptor transcription pathway
|
WikiPathways
|
SIDS Susceptibility Pathways
|
Ovarian Infertility Genes
|
Integrated Pancreatic Cancer Pathway
|
Nuclear ReceptorsWP712:Estrogen signaling pathway
|
Nuclear Receptors Meta-Pathway
|
Estrogen Receptor Pathway
|
Signaling by ERBB4
|
JAK/STAT
|
Leptin signaling pathway
|
miR-targeted genes in muscle cell - TarBase
|
Integrated Breast Cancer Pathway
|
Nuclear Receptors
|
References |
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |