Drug Information

Drug General Information
Drug ID
DXF3TP
Drug Name
6-{4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-2-[(pyridin-3-ylmethyl)-carbamoyl]-piperazin-1-yl}-6-oxo-hexanoic acid methyl ester
Synonyms
CHEMBL201817
Indication Discovery agent Investigative [1587926]
Formula
C32H35BrClN5O4
Canonical SMILES
COC(=O)CCCCC(=O)N1CCN(CC1C(=O)NCc2cccnc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C32H35BrClN5O4/c1-43-29(41)7-3-2-6-28(40)39-14-13-38(20-27(39)32(42)37-18-21-5-4-12-35-17-21)31-26-11-10-25(34)16-22(26)8-9-23-15-24(33)19-36-30(23)31/h4-5,10-12,15-17,19,27,31H,2-3,6-9,13-14,18,20H2,1H3,(H,37,42)
InChIKey
WPZXABAVFMGYIS-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.