| Drug General Information |
| Drug ID |
DX9W3N
|
| Drug Name |
9-Fluoro-2,2,4-trimethyl-5-((Z)-3-methyl-but-2-enylidene)-2,5-dihydro-1H-6-oxa-1-aza-chrysene
|
| Synonyms |
CHEMBL65690
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C24H24FNO
|
| Canonical SMILES |
CC(=C\\C=C\\1/Oc2ccc(F)cc2c3ccc4NC(C)(C)C=C(C)c4c13)C
|
| InChI |
InChI=1S/C24H24FNO/c1-14(2)6-10-21-23-17(18-12-16(25)7-11-20(18)27-21)8-9-19-22(23)15(3)13-24(4,5)26-19/h6-13,26H,1-5H3/b21-10-
|
| InChIKey |
VRWXHHASXOUVMH-FBHDLOMBSA-N
|
| Target and Pathway |
| Target(s) |
Progesterone receptor |
Target Info |
|
[1]
|
|---|
| mRNA of androgen receptor |
Target Info |
|
[1]
|
|
KEGG Pathway
|
Oocyte meiosis
|
|
Progesterone-mediated oocyte maturationhsa04114:Oocyte meiosis
|
|
Pathways in cancer
|
|
Prostate cancer
|
|
NetPath Pathway
|
EGFR1 Signaling Pathway
|
|
AndrogenReceptor Signaling Pathway
|
|
FSH Signaling Pathway
|
|
Pathway Interaction Database
|
Cellular roles of Anthrax toxinsmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
|
|
Coregulation of Androgen receptor activity
|
|
Regulation of Androgen receptor activity
|
|
Nongenotropic Androgen signaling
|
|
Regulation of nuclear beta catenin signaling and target gene transcription
|
|
FOXA1 transcription factor network
|
|
Notch-mediated HES/HEY network
|
|
Reactome
|
Nuclear signaling by ERBB4
|
|
Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
|
|
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
|
|
WikiPathways
|
Ovarian Infertility Genes
|
|
Signaling by ERBB4
|
|
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
|
|
Integrated Pancreatic Cancer Pathway
|
|
Prostate Cancer
|
|
Integrated Breast Cancer Pathway
|
|
Nuclear Receptors
|
|
Androgen receptor signaling pathway
|
| References |
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |
|---|
