Drug General Information
Drug ID
DX4MLT
Drug Name
Methyl 2-Butyl-4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methylpyridine-3-carboxylate
Synonyms
CHEMBL1215480
Indication Discovery agent Investigative [1587926]
Formula
C19H21ClN2O2
Canonical SMILES
CCCCC1=C(C(C(=C(C)N1)C#N)c2ccccc2Cl)C(=O)OC
InChI
InChI=1S/C19H21ClN2O2/c1-4-5-10-16-18(19(23)24-3)17(14(11-21)12(2)22-16)13-8-6-7-9-15(13)20/h6-9,17,22H,4-5,10H2,1-3H3
InChIKey
BUUOLGKPFRELSS-UHFFFAOYSA-N
Target and Pathway
Target(s) Progesterone receptor Target Info [1587926]
mRNA of androgen receptor Target Info [1587926]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturationhsa04114:Oocyte meiosis
Pathways in cancer
Prostate cancer
NetPath Pathway EGFR1 Signaling Pathway
AndrogenReceptor Signaling Pathway
FSH Signaling Pathway
Pathway Interaction Database Cellular roles of Anthrax toxinsmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
Nongenotropic Androgen signaling
Regulation of nuclear beta catenin signaling and target gene transcription
FOXA1 transcription factor network
Notch-mediated HES/HEY network
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
Integrated Pancreatic Cancer Pathway
Prostate Cancer
Integrated Breast Cancer Pathway
Nuclear Receptors
Androgen receptor signaling pathway
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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