Drug Information
| Drug General Information | |||||
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| Drug ID |
DX6NKK
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| Drug Name |
N-((S)-3-cyclohexyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)furan-2-carboxamide
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| Synonyms |
CHEMBL1807647
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H34N4O6S
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| Canonical SMILES |
C[C@@H]1CC[C@H](NC(=O)[C@H](CC2CCCCC2)NC(=O)c3occc3)C(=O)CN1S(=O)(=O)c4ccccn4
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| InChI |
InChI=1S/C26H34N4O6S/c1-18-12-13-20(22(31)17-30(18)37(34,35)24-11-5-6-14-27-24)28-25(32)21(16-19-8-3-2-4-9-19)29-26(33)23-10-7-15-36-23/h5-7,10-11,14-15,18-21H,2-4,8-9,12-13,16-17H2,1H3,(H,28,32)(H,29,33)/t18-,20+,21+/m1/s1
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| InChIKey |
KZCODYXMOKIMLT-GIVPXCGWSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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