Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXP8FN
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| Drug Name |
N-((S)-3-cyclopentyl-1-oxo-1-((S)-1-(4-(trifluoromethoxy)phenylamino)propan-2-ylamino)propan-2-yl)morpholine-4-carboxamide
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| Synonyms |
CHEMBL385534
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H33F3N4O4
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| Canonical SMILES |
C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC2CCCC2)NC(=O)N3CCOCC3
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| InChI |
InChI=1S/C23H33F3N4O4/c1-16(15-27-18-6-8-19(9-7-18)34-23(24,25)26)28-21(31)20(14-17-4-2-3-5-17)29-22(32)30-10-12-33-13-11-30/h6-9,16-17,20,27H,2-5,10-15H2,1H3,(H,28,31)(H,29,32)/t16-,20-/m0/s1
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| InChIKey |
FACZKPNWAPPTMQ-JXFKEZNVSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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