Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXL3UF
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| Drug Name |
N-((S)-4-cyclohexyl-1-((2R,3R)-1-(5-fluoroindolin-1-yl)-3-hydroxybutan-2-ylamino)-1-oxobutan-2-yl)-3-methoxybenzamide
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| Synonyms |
CHEMBL205566
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H40FN3O4
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| Canonical SMILES |
COc1cccc(c1)C(=O)N[C@@H](CCC2CCCCC2)C(=O)N[C@H](CN3CCc4cc(F)ccc34)[C@@H](C)O
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| InChI |
InChI=1S/C30H40FN3O4/c1-20(35)27(19-34-16-15-22-17-24(31)12-14-28(22)34)33-30(37)26(13-11-21-7-4-3-5-8-21)32-29(36)23-9-6-10-25(18-23)38-2/h6,9-10,12,14,17-18,20-21,26-27,35H,3-5,7-8,11,13,15-16,19H2,1-2H3,(H,32,36)(H,33,37)/t20-,26+,27-/m1/s1
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| InChIKey |
WDFFUHXXXVWAOH-JAMKYWPSSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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