Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXJT3H
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| Drug Name |
N-(2-chloro-5-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)-3-isopropylbenzamide
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| Synonyms |
CHEMBL246151
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H25ClN4O2
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| Canonical SMILES |
CNc1cc(ccn1)c2cccnc2Oc3ccc(Cl)c(NC(=O)c4cccc(c4)C(C)C)c3
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| InChI |
InChI=1S/C27H25ClN4O2/c1-17(2)18-6-4-7-20(14-18)26(33)32-24-16-21(9-10-23(24)28)34-27-22(8-5-12-31-27)19-11-13-30-25(15-19)29-3/h4-17H,1-3H3,(H,29,30)(H,32,33)
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| InChIKey |
SBRDWSXZGGLNQG-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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