Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXTK8N
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| Drug Name |
N-{(S)-2-Cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-4-[1,2,4]triazol-1-yl-benzamide
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| Synonyms |
CHEMBL196673
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H34N6O3
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3ccc(cc3)n4cncn4)cc1
|
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| InChI |
InChI=1S/C27H34N6O3/c1-36-24-13-9-22(10-14-24)29-15-16-30-27(35)25(17-20-5-3-2-4-6-20)32-26(34)21-7-11-23(12-8-21)33-19-28-18-31-33/h7-14,18-20,25,29H,2-6,15-17H2,1H3,(H,30,35)(H,32,34)/t25-/m0/s1
|
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| InChIKey |
KOLZVLRWUSMIPM-VWLOTQADSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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