Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5STX
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| Drug Name |
N-Isopropyl-2-[(3R,5S,7R)-2-oxo-7-phenyl-5-o-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide
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| Synonyms |
CHEMBL319569
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| Indication | Discovery agent | Investigative | [1] | ||
| Formula |
C32H38N4O3
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| Canonical SMILES |
CC(C)NC(=O)CN1[C@H](C[C@H](C[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)c3ccccc3C)c4ccccc4
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| InChI |
InChI=1S/C32H38N4O3/c1-21(2)33-30(37)20-36-29(24-13-6-5-7-14-24)19-25(27-16-9-8-12-23(27)4)18-28(31(36)38)35-32(39)34-26-15-10-11-22(3)17-26/h5-17,21,25,28-29H,18-20H2,1-4H3,(H,33,37)(H2,34,35,39)/t25-,28+,29+/m0/s1
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| InChIKey |
MIUNVYQVNGDVKG-RFYMFKDESA-N
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| Target and Pathway | |||||
| Target(s) | Gastrin/cholecystokinin type B receptor | Target Info | [1] | ||
| Cholecystokinin receptor type A | Target Info | [1] | |||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gastric acid secretionhsa04020:Calcium signaling pathway | |||||
| Insulin secretion | |||||
| Pancreatic secretion | |||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like | |||||
| References | |||||
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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