| Drug General Information |
| Drug ID |
DXA2ET
|
| Drug Name |
SID48410082
|
| Synonyms |
CHEMBL1448985
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C25H19N3O3
|
| Canonical SMILES |
O=C(NCCc1ccccc1)c2ccc3nc(c4occc4)c(nc3c2)c5occc5
|
| InChI |
InChI=1S/C25H19N3O3/c29-25(26-13-12-17-6-2-1-3-7-17)18-10-11-19-20(16-18)28-24(22-9-5-15-31-22)23(27-19)21-8-4-14-30-21/h1-11,14-16H,12-13H2,(H,26,29)
|
| InChIKey |
PNWLIGGQZQMFPW-UHFFFAOYSA-N
|
| Target and Pathway |
| Target(s) |
Estrogen receptor beta |
Target Info |
|
[1]
|
|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 |
Target Info |
|
[1]
|
|
KEGG Pathway
|
Estrogen signaling pathway
|
|
Prolactin signaling pathwayhsa04151:PI3K-Akt signaling pathway
|
|
MicroRNAs in cancer
|
|
NetPath Pathway
|
TCR Signaling Pathway
|
|
PANTHER Pathway
|
Apoptosis signaling pathway
|
|
CCKR signaling map ST
|
|
Pathway Interaction Database
|
Plasma membrane estrogen receptor signaling
|
|
Validated nuclear estrogen receptor beta network
|
|
Validated nuclear estrogen receptor alpha networke2f_pathway:E2F transcription factor network
|
|
Direct p53 effectors
|
|
IL6-mediated signaling events
|
|
HIF-1-alpha transcription factor network
|
|
Reactome
|
Nuclear Receptor transcription pathway
|
|
WikiPathways
|
SIDS Susceptibility Pathways
|
|
Ovarian Infertility Genes
|
|
Integrated Pancreatic Cancer Pathway
|
|
Nuclear ReceptorsWP254:Apoptosis
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in leukocytes - TarBase
|
|
Apoptosis Modulation and Signaling
|
| References |
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |
|---|
