Drug General Information |
Drug ID |
DXWD5M
|
Drug Name |
SID857522
|
Synonyms |
CHEMBL3189821
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Formula |
C22H16N2O5
|
Canonical SMILES |
COc1ccc(OC)c(\\C=N\\c2oc(c3occc3)c(c4occc4)c2C#N)c1
|
InChI |
InChI=1S/C22H16N2O5/c1-25-15-7-8-17(26-2)14(11-15)13-24-22-16(12-23)20(18-5-3-9-27-18)21(29-22)19-6-4-10-28-19/h3-11,13H,1-2H3/b24-13+
|
InChIKey |
VPFUWGGRSSAAIQ-ZMOGYAJESA-N
|
Target and Pathway |
Target(s) |
Estrogen receptor beta |
Target Info |
|
[1]
|
Induced myeloid leukemia cell differentiation protein Mcl-1 |
Target Info |
|
[1]
|
KEGG Pathway
|
Estrogen signaling pathway
|
Prolactin signaling pathwayhsa04151:PI3K-Akt signaling pathway
|
MicroRNAs in cancer
|
NetPath Pathway
|
TCR Signaling Pathway
|
PANTHER Pathway
|
Apoptosis signaling pathway
|
CCKR signaling map ST
|
Pathway Interaction Database
|
Plasma membrane estrogen receptor signaling
|
Validated nuclear estrogen receptor beta network
|
Validated nuclear estrogen receptor alpha networke2f_pathway:E2F transcription factor network
|
Direct p53 effectors
|
IL6-mediated signaling events
|
HIF-1-alpha transcription factor network
|
Reactome
|
Nuclear Receptor transcription pathway
|
WikiPathways
|
SIDS Susceptibility Pathways
|
Ovarian Infertility Genes
|
Integrated Pancreatic Cancer Pathway
|
Nuclear ReceptorsWP254:Apoptosis
|
miR-targeted genes in muscle cell - TarBase
|
miR-targeted genes in lymphocytes - TarBase
|
miR-targeted genes in leukocytes - TarBase
|
Apoptosis Modulation and Signaling
|
References |
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |