Drug Information

Drug General Information
Drug ID
D0S9UQ
Former ID
DIB019921
Drug Name
GMQ
Synonyms
2-guanidine-4-methylquinazoline; GNF-Pf-3515; 2-GMQ
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467537]
Structure
Download
2D MOL
Formula
C10H11N5
InChI
InChI=1S/C10H11N5/c1-6-7-4-2-3-5-8(7)14-10(13-6)15-9(11)12/h2-5H,1H3,(H4,11,12,13,14,15)
InChIKey
ONQKSKDLYYDFLL-UHFFFAOYSA-N
PubChem Compound ID
345657
PubChem Substance ID
473784, 3308779, 3898606, 5436241, 5940767, 11500131, 12012126, 12339506, 14797505, 24820975, 41492701, 51763617, 57713289, 81093413, 85818118, 88198413, 88518533, 92289236, 103709741, 104568469, 104819002, 117407384, 124504262, 125076868, 125085654, 125398613, 130965400, 131337617, 131362171, 143038297, 143420591, 162655819, 163177176, 163340229, 164237620, 170192574, 170481078, 178101020, 178123969, 179065365, 179083506, 181741301, 187577919, 223362506, 223818296, 225178693, 228450084, 241129534, 247982832, 252508611
Target and Pathway
Target(s) Acid-sensing ion channel ASIC3 Target Info Activator [543915]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome Stimuli-sensing channels
WikiPathways Iron uptake and transport
References
Ref 467537(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4203).
Ref 543915(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 686).

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