Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D09WED
|
||||
Former ID |
DNC010152
|
||||
Drug Name |
Kuwanon R
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Discovery agent | Investigative | [1] | ||
Structure |
Download2D MOL |
||||
Formula |
C40H38O9
|
||||
Canonical SMILES |
CC1=CC(C(C(C1)C2=C(C=C(C=C2)O)O)C(=O)C3=CC(=C(C(=C3)O)C<br />C=C(C)C)O)C4=C(C=CC(=C4O)C(=O)C=CC5=CC=C(C=C5)O)O
|
||||
InChI |
1S/C40H38O9/c1-21(2)4-11-28-34(45)18-24(19-35(28)46)39(48)37-30(27-12-10-26(42)20-36(27)47)16-22(3)17-31(37)38-33(44)15-13-29(40(38)49)32(43)14-7-23-5-8-25(41)9-6-23/h4-10,12-15,17-20,30-31,37,41-42,44-47,49H,11,16H2,1-3H3/b14-7+/t30-,31+,37-/m1/s1
|
||||
InChIKey |
PXFKYAIDSYKIJA-DLBCFTNOSA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | mRNA of Protein tyrosine phosphatase-1B | Target Info | Inhibitor | [1] | |
KEGG Pathway | Adherens junction | ||||
Insulin signaling pathway | |||||
NetPath Pathway | FSH Signaling Pathway | ||||
PANTHER Pathway | Cadherin signaling pathway | ||||
Pathway Interaction Database | Insulin Pathway | ||||
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | |||||
Signaling events mediated by PTP1B | |||||
Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
Signaling events mediated by TCPTP | |||||
IGF1 pathway | |||||
EGF receptor (ErbB1) signaling pathway | |||||
Posttranslational regulation of adherens junction stability and dissassembly | |||||
PDGFR-beta signaling pathway | |||||
N-cadherin signaling events | |||||
Reactome | Integrin alphaIIb beta3 signaling | ||||
Regulation of IFNG signaling | |||||
Regulation of IFNA signaling | |||||
Growth hormone receptor signaling | |||||
WikiPathways | Insulin Signaling | ||||
Growth hormone receptor signaling | |||||
Leptin signaling pathway | |||||
Interferon gamma signaling | |||||
Interferon alpha/beta signaling | |||||
Integrin alphaIIb beta3 signaling | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2009 Dec 1;19(23):6759-61. Epub 2009 Oct 7.Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.