Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04FQZ
|
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| Former ID |
DNC007840
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| Drug Name |
4-(4-hexylphenyl)-4-oxobut-2-enoic acid
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C16H20O3
|
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| Canonical SMILES |
CCCCCCC1=CC=C(C=C1)C(=O)C=CC(=O)O
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| InChI |
1S/C16H20O3/c1-2-3-4-5-6-13-7-9-14(10-8-13)15(17)11-12-16(18)19/h7-12H,2-6H2,1H3,(H,18,19)/b12-11-
|
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| InChIKey |
HKEVTQICMJNUNY-QXMHVHEDSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thyroid hormone receptor alpha | Target Info | Inhibitor | [1] | |
| Thyroid hormone receptor beta-1 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction | |||||
| Thyroid hormone signaling pathway | |||||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor | ||||
| Reactome | Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway | ||||
| WikiPathways | Endochondral Ossification | ||||
| Nuclear ReceptorsWP706:SIDS Susceptibility Pathways | |||||
| Hematopoietic Stem Cell Differentiation | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships. | ||||
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