| Drug General Information |
| Drug ID |
D08ISP
|
| Former ID |
DNC005007
|
| Drug Name |
5-Methyl-4-propyl-pyrrolidin-(2Z)-ylideneamine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C8H16N2
|
| Canonical SMILES |
CCCC1CC(=NC1C)N
|
| InChI |
1S/C8H16N2/c1-3-4-7-5-8(9)10-6(7)2/h6-7H,3-5H2,1-2H3,(H2,9,10)
|
| InChIKey |
KBOKLILFNBAIHC-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Nitric oxide synthase, inducible |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Citrulline-nitric oxide cycle
|
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KEGG Pathway
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Arginine biosynthesis
|
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Arginine and proline metabolism
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Metabolic pathways
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Calcium signaling pathway
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HIF-1 signaling pathway
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Peroxisome
|
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Salmonella infection
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Pertussis
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Leishmaniasis
|
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Amoebiasis
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Tuberculosis
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Pathways in cancer
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Small cell lung cancer
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NetPath Pathway
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IL1 Signaling Pathway
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IL2 Signaling Pathway
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Pathway Interaction Database
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IL12-mediated signaling events
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Alpha9 beta1 integrin signaling events
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ATF-2 transcription factor network
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IL23-mediated signaling events
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Signaling mediated by p38-alpha and p38-beta
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HIF-1-alpha transcription factor network
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Reactome
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ROS production in response to bacteria
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Nitric oxide stimulates guanylate cyclase
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WikiPathways
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Type II interferon signaling (IFNG)
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Spinal Cord Injury
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AGE/RAGE pathway
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Effects of Nitric Oxide
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| References |
| REF 1 | Bioorg Med Chem Lett. 2004 Sep 6;14(17):4539-44.Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase. |
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