Drug General Information |
Drug ID |
D03SLR
|
Former ID |
DNC010453
|
Drug Name |
FERULIC ACID
|
Drug Type |
Small molecular drug
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C10H10O4
|
Canonical SMILES |
COC1=C(C=CC(=C1)C=CC(=O)O)O
|
InChI |
1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+
|
InChIKey |
KSEBMYQBYZTDHS-HWKANZROSA-N
|
PubChem Compound ID |
|
Target and Pathway |
Target(s) |
Carbonic anhydrase XII |
Target Info |
Inhibitor |
[1]
|
Carbonic anhydrase II |
Target Info |
Inhibitor |
[1]
|
Carbonic anhydrase XIV |
Target Info |
Inhibitor |
[1]
|
Carbonic anhydrase IX |
Target Info |
Inhibitor |
[1]
|
Carbonic anhydrase VI |
Target Info |
Inhibitor |
[1]
|
Carbonic anhydrase I |
Target Info |
Inhibitor |
[1]
|
Carbonic anhydrase IV |
Target Info |
Inhibitor |
[1]
|
Carbonic anhydrase |
Target Info |
Inhibitor |
[1]
|
KEGG Pathway
|
Nitrogen metabolismhsa00910:Nitrogen metabolism
|
Proximal tubule bicarbonate reclamation
|
Collecting duct acid secretion
|
Gastric acid secretion
|
Pancreatic secretion
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Bile secretionhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolism
|
NetPath Pathway
|
TGF_beta_Receptor Signaling PathwayNetPath_16:IL4 Signaling Pathway
|
EGFR1 Signaling Pathway
|
Pathway Interaction Database
|
HIF-1-alpha transcription factor networkcmyb_pathway:C-MYB transcription factor network
|
PathWhiz Pathway
|
Gastric Acid Production
|
Reactome
|
Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen
|
Erythrocytes take up oxygen and release carbon dioxide
|
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1234158:Regulation of gene expression by Hypoxia-inducible Factor
|
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen
|
Reversible hydration of carbon dioxide
|
WikiPathways
|
Reversible Hydration of Carbon Dioxide
|
miR-targeted genes in muscle cell - TarBase
|
miR-targeted genes in leukocytes - TarBase
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miR-targeted genes in epithelium - TarBaseWP2770:Reversible Hydration of Carbon Dioxide
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Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
|
Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon DioxideWP2877:Vitamin D Receptor Pathway
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Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon DioxideWP2770:Reversible Hydration of Carbon Dioxide
|
Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide
|
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
|
References |
REF 1 | Bioorg Med Chem. 2010 Mar 15;18(6):2159-64. Epub 2010 Feb 6.Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. |