Drug Information

Drug General Information
Drug ID
D0W6PP
Former ID
DNC000673
Drug Name
Galnon
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541334]
Structure
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2D MOL

3D MOL
Formula
C40H46N4O6
InChI
InChI=1S/C40H46N4O6/c1-25-21-37(45)50-36-23-27(18-19-28(25)36)42-38(46)34(17-9-10-20-41)43-39(47)35(22-26-11-3-2-4-12-26)44-40(48)49-24-33-31-15-7-5-13-29(31)30-14-6-8-16-32(30)33/h5-8,13-16,18-19,21,23,26,33-35H,2-4,9-12,17,20,22,24,41H2,1H3,(H,42,46)(H,43,47)(H,44,48)/t34-,35-/m0/s1
InChIKey
IKNOZZKXIDSTRN-PXLJZGITSA-N
CAS Number
CAS 220322-05-4
PubChem Compound ID
5311268
PubChem Substance ID
7979851, 11056392, 29217556, 39340970, 52443175, 57359411, 103730331, 104117513, 104161609, 114155709, 134340041, 135698498, 178102739, 230390610, 241083897, 241375770, 249617482, 252156289
Target and Pathway
Target(s) Galanin receptor type 1 Target Info Agonist [535451]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 541334(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6118).
Ref 535451Anticonvulsant activity of a nonpeptide galanin receptor agonist. Proc Natl Acad Sci U S A. 2002 May 14;99(10):7136-41.

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