Drug Information

Drug General Information
Drug ID
D06PSS
Former ID
DAP000918
Drug Name
Nateglinide
Synonyms
Fastic; IPCCPA; Senaglinide; Starlix; Starsis; Trazec; Nateglinide [INN]; Novartis brand of nateglinide; DJN 608; A-4166; AY-4166; DJN-608; Nate-glinide; Starlix (TN); YM-026; SDZ-DJN-608; N-((4-isopropylcyclohexyl)carbonyl)phenylalanine; Nateglinide, (D-Phe)-isomer; Nateglinide, (cis,D-Phe)-isomer; N-{[4-(propan-2-yl)cyclohexyl]carbonyl}phenylalanine; N-{[trans-4-(propan-2-yl)cyclohexyl]carbonyl}-D-phenylalanine; (2R)-3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid; 3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid
Drug Type
Small molecular drug
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Approved [536361], [541914]
Therapeutic Class
Hypoglycemic Agents
Company
Norvatis Phamaceuticals Corporation
Structure
Download
2D MOL

3D MOL
Formula
C19H27NO3
InChI
InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1
InChIKey
OELFLUMRDSZNSF-BRWVUGGUSA-N
CAS Number
CAS 105816-04-4
PubChem Compound ID
5311309
PubChem Substance ID
582898, 7848174, 7980094, 12013966, 14752539, 14874578, 26719880, 37101837, 39341005, 46386701, 46504836, 49681657, 49830241, 56313768, 57359430, 75919327, 81092826, 91748929, 92308370, 92308686, 92711649, 93166415, 103206766, 104253649, 114155796, 117890894, 124658899, 124757828, 124801358, 125164632, 126630653, 126657177, 128797137, 128797139, 128797141, 131293719, 131347903, 131860350, 135692483, 136949105, 137129256, 137175459, 137231395, 140330680, 142491149, 142619974, 143248460, 144204985, 151981031, 152100318
SuperDrug ATC ID
A10BX03
SuperDrug CAS ID
cas=105816044
Target and Pathway
Target(s) Potassium channel Target Info Modulator [556264]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 541914(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6833).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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