Drug General Information
Drug ID	D0IB8N
Former ID	DNC001034
Drug Name	Noradrenalone (arterenone)
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[535831]
Structure		Download 2D MOL 3D MOL
Formula	C8H9NO3
Canonical SMILES	C1=CC(=C(C=C1C(=O)CN)O)O
InChI	1S/C8H9NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,10-11H,4,9H2
InChIKey	CNFQARFTXUBHJY-UHFFFAOYSA-N
CAS Number	CAS 51-41-2
PubChem Compound ID	10359
PubChem Substance ID	219188, 5455497, 8157477, 29228863, 49863333, 57326158, 77706762, 103114947, 104323081, 117562120, 125684122, 127649776, 132557651, 134977782, 138836816, 162860154, 172876736, 196384250, 227886773
ChEBI ID	ChEBI:18357
Target and Pathway
Target(s)	Aromatic-L-amino-acid decarboxylase	Target Info	Activator	[535831]
BioCyc Pathway	Superpathway of tryptophan utilization
	Tryptophan degradation via tryptamine
	Serotonin and melatonin biosynthesis
	Catecholamine biosynthesis
KEGG Pathway	Histidine metabolism
	Tyrosine metabolism
	Phenylalanine metabolism
	Tryptophan metabolism
	Metabolic pathways
	Serotonergic synapse
	Dopaminergic synapse
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	5-Hydroxytryptamine biosynthesis
	Dopamine receptor mediated signaling pathway
	Nicotine pharmacodynamics pathway
PathWhiz Pathway	Catecholamine Biosynthesis
	Tyrosine Metabolism
	Tryptophan Metabolism
WikiPathways	SIDS Susceptibility Pathways
	Biogenic Amine Synthesis
	Tryptophan metabolism
	Dopaminergic Neurogenesis
	Metabolism of amino acids and derivatives
	Dopamine metabolism
	Parkinsons Disease Pathway
	Nicotine Activity on Dopaminergic Neurons
References
Ref 535831	Activation of an adrenergic pro-drug through sequential stereoselective action of tandem target enzymes. Biochem Biophys Res Commun. 1992 Nov 30;189(1):33-9.
Ref 535831	Activation of an adrenergic pro-drug through sequential stereoselective action of tandem target enzymes. Biochem Biophys Res Commun. 1992 Nov 30;189(1):33-9.

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