Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02SQF
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| Former ID |
DIB018623
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| Drug Name |
4-methylhistamine
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C6H11N3
|
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| InChI |
InChI=1S/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9)
|
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| InChIKey |
UGYXPZQILZRKJJ-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
8175026, 15218924, 34678762, 47285816, 48029603, 49846694, 49979068, 57312047, 78084230, 84974637, 85083159, 85208920, 96024150, 103173326, 104326639, 126663318, 129366978, 134999313, 135649802, 137005456, 141766906, 142022261, 148176123, 162219797, 164174740, 170521455, 177748554, 179294129, 198955968, 216076725, 223668744, 224932212, 226909039, 236636659, 241065799, 249539400, 249769736, 249963149, 251874886
|
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| Target and Pathway | |||||
| Target(s) | Histamine H4 receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCR ligand binding | ||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1269). | ||||
| REF 2 | Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives. Br J Pharmacol. 2006 Apr;147(7):744-54. | ||||
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