Drug Information

Drug General Information
Drug ID
D00RDY
Former ID
DNC000089
Drug Name
5'-iodotubercidin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [536049]
Structure
Download
2D MOL

3D MOL
Formula
C11H13IN4O4
Canonical SMILES
C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)I
InChI
1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
InChIKey
WHSIXKUPQCKWBY-IOSLPCCCSA-N
CAS Number
CAS 24386-93-4
PubChem Compound ID
97297
PubChem Substance ID
814098, 7979324, 8142631, 10228828, 15376461, 44427634, 46506259, 46530621, 50070345, 50070993, 53776847, 57336426, 57551400, 77287794, 85182436, 103059250, 103312988, 104121467, 104420528, 119525449, 121270651, 123121566, 134223996, 134964993, 135054302, 135697851, 135935198, 137014326, 152258715, 160643784, 160647550, 160854744, 160967600, 164043857, 165246158, 170481936, 175613967, 180096528, 186014773, 223384617, 223703164, 224057599, 226657244, 241043890, 241375590, 252156059, 252214541, 252418448, 252465658
Target and Pathway
Target(s) Adenosine kinase Target Info Inhibitor [536049]
BioCyc Pathway Superpathway of purine nucleotide salvage
Adenine and adenosine salvage II
KEGG Pathway Purine metabolism
Metabolic pathways
Reactome Purine salvage
WikiPathways Metabolism of nucleotides
References
Ref 536049Inhibition of adenosine kinase attenuates interleukin-1- and lipopolysaccharide-induced alterations in articular cartilage metabolism. Osteoarthritis Cartilage. 2005 Mar;13(3):250-7.
Ref 536049Inhibition of adenosine kinase attenuates interleukin-1- and lipopolysaccharide-induced alterations in articular cartilage metabolism. Osteoarthritis Cartilage. 2005 Mar;13(3):250-7.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.