Drug General Information
Drug ID	D08MKF
Former ID	DNC001017
Drug Name	Nickel chloride
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538044]
Structure		Download 2D MOL 3D MOL
Formula	Cl2Ni
Canonical SMILES	Cl[Ni]Cl
InChI	1S/2ClH.Ni/h2*1H;/q;;+2/p-2
InChIKey	QMMRZOWCJAIUJA-UHFFFAOYSA-L
CAS Number	CAS 7718-54-9
PubChem Compound ID	24385
PubChem Substance ID	138091, 599833, 6718687, 8167797, 10535469, 15995108, 24434799, 24860636, 24868610, 29291457, 49997313, 53787722, 56370154, 57331687, 74788158, 91693525, 104359844, 125824411, 134340282, 134989178, 137005957, 142398023, 144212492, 162240580, 162271138, 162509726, 164779286, 164779295, 176258544, 204363565, 223719324, 223752703
ChEBI ID	ChEBI:34887
Target and Pathway
Target(s)	Voltage-dependent T-type calcium channel alpha-1G subunit	Target Info	Blocker	[538044]
KEGG Pathway	MAPK signaling pathway
	Calcium signaling pathway
	Circadian entrainment
	Type II diabetes mellitus
PANTHER Pathway	Endogenous cannabinoid signaling
	GABA-B receptor II signaling
	Nicotine pharmacodynamics pathway
Pathway Interaction Database	Regulation of nuclear beta catenin signaling and target gene transcription
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	NCAM1 interactions
WikiPathways	NCAM signaling for neurite out-growth
	Nicotine Activity on Chromaffin Cells
References
Ref 538044	T-type calcium channels facilitate insulin secretion by enhancing general excitability in the insulin-secreting beta-cell line, INS-1. Endocrinology. 1997 Sep;138(9):3735-40.
Ref 538044	T-type calcium channels facilitate insulin secretion by enhancing general excitability in the insulin-secreting beta-cell line, INS-1. Endocrinology. 1997 Sep;138(9):3735-40.

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